MSK1 (Ab-376) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityMSK1 (Ab-376)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatepitope affinity purified
Size0.05 mL, 0.1 mL
Concentration1.0 mg/ml
ApplicationsWestern Blot (WB)
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DescriptionThe antibody detects endogenous level of total MSK1 protein. Serine/threonine kinase required for the mitogen or stress-induced phosphorylation of the transcription factors CREB (cAMP response element-binding protein) and ATF1 (activating transcription factor-1). Essential role in the control of RELA transcriptional activity in response to TNF. Directly represses transcription via phosphorylation of 'Ser-1' of histone H2A. Phosphorylates 'Ser-10' of histone H3 in response to mitogenics, stress stimuli and epidemal growth-factor (EGF), which results in the transcriptional activation of several immediate early genes, including proto-oncogenes c-fos/FOS and c-jun/JUN. May also phosphorylate 'Ser-28' of histone H3. Mediates the mitogen- and str
ImmunogenImmunogen Type: Peptide-KLH Immunogen Description: Peptide sequence around aa.374~378 (G-Y-S-F-V) derived from Human MSK1.
Other Names[MSPK1; RPS6KA5]
Gene, Accession #[MSK1], Gene ID: 9252, NCBI: NP_004746.2, UniProt: O75582
Catalog #MBS9414131
Price$200, $255
Order / More InfoMSK1 (Ab-376) Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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