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Antigenic Specificity | KPNB1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.1 mL |
Concentration | 2.6 mg/ml |
Applications | Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total KPNB1 protein. Nucleocytoplasmic transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. The import of proteins containing a nuclear localization signal (NLS) requires the NLS import receptor, a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex. In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore complex and the importin subunits dissociate. Importin alpha enters the nucleoplasm |
Immunogen | Immunogen Type: Peptide Immunogen Description: Synthetic peptide corresponding to a region derived from internal residues of human karyopherin (importin) beta 1 |
Other Names | [IMB1; IPO1; IPOB; Impnb; NTF97] |
Gene, Accession # | [KPNB1], Gene ID: 3837, NCBI: NP_001263382.1, UniProt: Q14974 |
Catalog # | MBS9409598 |
Price | $255 |
Order / More Info | KPNB1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |