MARK1/2/3/4 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityMARK1/2/3/4
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat, monkey
Isotypen/a
Formatimmunogen affinity purified
Size0.03 mL, 0.1 mL, 0.2 mL
Concentration1 mg/ml
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC) Paraffin, Immunofluorescence (IF), ELISA (EIA)
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DescriptionSpecificity: MARK1/2/3/4 Polyclonal Antibody detects endogenous levels of MARK1/2/3/4 protein. MARK1 is a Protein Coding gene. Serine/threonine-protein kinase MARK1 involved in cell polarity and microtubule dynamics regulation. Phosphorylates DCX, MAP2, MAP4 and MAPT/TAU. Involved in cell polarity by phosphorylating the microtubule-associated proteins MAP2, MAP4 and MAPT/TAU at KXGS motifs, causing detachment from microtubules, and their disassembly. Involved in the regulation of neuronal migration through its dual activities in regulating cellular polarity and microtubule dynamics, possibly by phosphorylating and regulating DCX. Also acts as a positive regulator of the Wnt signaling pathway, probably by mediating phosphorylation of disheve
ImmunogenImmunogen: Synthesized peptide derived from human MARK1/2/3/4 around the non-phosphorylation site of T215
Other Names[Rabbit MARK1/2/3/4; MARK1; KIAA1477; MARK; Serine/threonine-protein kinase MARK1; MAP/microtubule affinity-regulating kinase 1; PAR1 homolog c; Par-1c; Par1c; MARK2; EMK1; Serine/threonine-protein kinase MARK2; ELKL motif kinase 1; EMK-1; MAP/microtubule affin]
Gene, Accession #[MARK1/2/3/4], Gene ID: 4139; 2011; 4140; 57787, NCBI: NP_061120.3, UniProt: Q9P0L2
Catalog #MBS9702441
Price$130, $220, $325
Order / More InfoMARK1/2/3/4 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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