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Antigenic Specificity | NogoA |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: At least five isoforms of Nogo are known to exist; this antibody is specific for NogoA. NogoA is a member of a family of integral membrane proteins termed reticulons that are thought to be involved in numerous disorders including neurodegenerative diseases. Reticulon proteins are known to regulate many cellular processes and interact with multiple proteins and receptors such as BACE. NogoA was initially identified as a myelin-associated neurite outgrowth inhibitor. It is highly expressed in oligodendrocytes in the white matter of the CNS; blocking its activity with antibodies or other factors results in improved axon regrowth and functional recovery in experimental CNS lesion models. NogoA has also been suggested to play a role |
Immunogen | Immunogen Type: Peptide Immunogen Description: Raised against a 23 amino acid peptide from near the amino terminus of human NogoA. |
Other Names | [Neurite outgrowth inhibitor A, reticulon 4, RTN4] |
Gene, Accession # | [NogoA], Gene ID: 57142, NCBI: NP_065393 |
Catalog # | MBS9411537 |
Price | $320 |
Order / More Info | NogoA Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |