IPO4 - middle region Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityIPO4 - middle region
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formataffinity purified
Size0.1 mL
Concentrationn/a
ApplicationsWestern Blot (WB)
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DescriptionFunctions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals (NLS) in cargo substrates. Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and
ImmunogenImmunogen: The immunogen is a synthetic peptide directed towards the middle region of human IPO4
Other Names[importin-4; Importin-4; importin-4; importin 4; Importin-4b; Imp4b; Ran-binding protein 4]
Gene, Accession #[IPO4], Gene ID: 79711, NCBI: NP_078934.3, UniProt: Q8TEX9
Catalog #MBS3222207
Price$335
Order / More InfoIPO4 - middle region Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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