Catenin, gamma (Cardiomyocyte Marker) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityCatenin, gamma (Cardiomyocyte Marker)
Clone[15F11]
Host SpeciesMouse
Reactive Specieshuman, mouse, cat, rat, chicken, cow, dog.
IsotypeIgG1, kappa
Formatunconjugated
Size0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml)
Concentrationn/a
ApplicationsFlow Cytometry (FC/FACS), Immunofluorescence (IF), Western Blot (WB)
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DescriptionSpecificity: It recognizes a protein of 80-87kDa, identified as gamma-catenin. The catenins (alpha, beta, gamma and delta) are ubiquitously expressed, cytoplasmic proteins that associate with E-cadherin at cellular junctions. Catenin/cadherin complexes play an important role in mediating cellular adhesion. alpha T-catenin, also referred to as VR22, is a 895-amino acid protein that is most abundantly expressed in cardio-myocytes and in the peritubular myoid cells of the testis. alpha T-catenin binds to alpha E-catenin as well as to beta-catenin, and it functions to inhibit Wnt signaling. CTNNA3, the gene that encodes for alpha-T-catenin, is located on chromosome 10, and mutations in this gene show a strong correlation to late-onset Alzheimer
ImmunogenImmunogen: Recombinant, full length chicken Catenin gamma protein Cellular Localization: Cell Surface and Cytoplasmic
Other Names[ARVD12; Catenin (cadherin-associated protein), gamma 80kDa; Catenin gamma; CTNNG; Desmoplakin III; Desmoplakin-3; DP3; DPIII; Junction Plakoglobin; PDGB; PKGB]
Gene, Accession #[JUP], Gene ID: 3728, NCBI: NP_002221.1, UniProt: P14923
Catalog #MBS4380057
Price$190, $340, $340
Order / More InfoCatenin, gamma (Cardiomyocyte Marker) Antibody from MYBIOSOURCE INC.
Product Specific ReferencesSacco, PA; McGranahan, TM; Wheelock, MJ; Johnson, KR. Identification of plakoglobin domains required for association with N-cadherin and alpha-catenin. J Biol Chem 1995, 270:20201-6. Johnson, KR; Lewis, JE; Li, D; Wahl, J; Soler, AP; Knudsen, KA; Wheelock, MJ. P- and E-cadherin are in separate complexes in cells expressing both cadherins. Exp Cell Res 1993, 207: 252-6.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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