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Antigenic Specificity | Human NFATC4 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | DyLight 488 conjugate |
Size | 0.1 mg |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: No cross reactivity with other proteins. Nuclear factor of activated T-cells, cytoplasmic 4 is a protein that in humans is encoded by the NFATC4 gene. This gene encodes a member of the nuclear factor of activated T cells (NFAT) protein family. The encoded protein is part of a DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor stimulation and an inducible nuclear component. NFAT proteins are activated by the calmodulin-dependent phosphatase, calcineurin. The encoded protein plays a role in the inducible expression of cytokine genes in T cells, especially in the induction of interleukin-2 and interleukin-4. |
Immunogen | Immunogen: E Coli-derived human NFATC4 recombinant protein (Position: Q413-D522). |
Other Names | [Rabbit IgG Human NFATC4 DyLight 488 Conjugated, Flow Validated; Nuclear factor of activated T-cells, cytoplasmic 4; NF-ATc4; NFATc4; T-cell transcription factor NFAT3; NF-AT3; NFATC4; NFAT3; Nuclear factor of activated T-cells 4] |
Gene, Accession # | [NFATC4], Gene ID: 4776, NCBI: NP_001129494.1, UniProt: Q14934 |
Catalog # | MBS1751427 |
Price | $330 |
Order / More Info | Human NFATC4 Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Hoey T, Sun YL, Williamson K, Xu X (May 1995). Isolation of two new members of the NF-AT gene family and functional characterization of the NF-AT proteins. Immunity. 2 (5): 461-72. 2. Yang T, Davis RJ, Chow CW (Oct 2001). Requirement of two NFATc4 transactivation domains for CBP potentiation. The Journal of Biological Chemistry. 276 (43): 39569-76. |