Phospho-SAPK/JNK Pathway Antibody Sampler Kit Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPhospho-SAPK/JNK Pathway Antibody Sampler Kit
Clonen/a
Host Speciesn/a
Reactive Speciesn/a
Isotypen/a
Formatunconjugated
Size1 kit
Concentrationn/a
ApplicationsWestern Blot (WB)
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DescriptionBackground: The stress-activated protein kinase/Jun-amino-terminal kinase SAPK/JNK is potently and preferentially activated by a variety of environmental stresses including UV and gamma radiation, ceramides, inflammatory cytokines, and in some instances, growth factors and GPCR agonists. As with the other MAPKs, the core signaling unit is composed of a MAPKKK, typically MEKK1-MEKK4, or by one of the mixed lineage kinases (MLKs), which phosphorylate and activate MKK4/7. Upon activation, MKKs phosphorylate and activate the SAPK/JNK kinase. Stress signals are delivered to this cascade by small GTPases of the Rho family (Rac, Rho, cdc42). Both Rac1 and cdc42 mediate the stimulation of MEKKs and MLKs. Alternatively, MKK4/7 can be activated in a
Immunogenn/a
Other Namesn/a
Gene, Accession #[SAPK/JNK]
Catalog #MBS2549991
Price$295
Order / More InfoPhospho-SAPK/JNK Pathway Antibody Sampler Kit Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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