Edit |   |
---|---|
Antigenic Specificity | CENPS |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of CENPS protein. CENPS (Centromere Protein S) was identified in the neuroblastoma tumor suppressor candidate region on chromosome 1p36. It contains a TFIID-31 domain, similar to that found in TATA box-binding protein-associated factor, TAF (II) 31, which is required for p53-mediated transcription activation. CENPS was expressed at very low levels in neuroblastoma tumors, and was shown to reduce cell growth in neuroblastoma cells, suggesting that it may have a role in a cell death pathway. The protein is a component of multiple complexes, including the Fanconi anemia (FA) core complex, the APITD1/CENPS complex, and the CENPA-CAD (nucleosome distal) complex. Known functions include an involvement with c |
Immunogen | Immunogen: Synthesized peptide derived from part region of human CENPS protein at amino acid sequence of 70-150 |
Other Names | [Rabbit CENPS; Centromere protein S; CENP-S; Apoptosis-inducing TAF9-like domain-containing protein 1; FANCM-associated histone fold protein 1; FANCM-interacting histone fold protein 1; Fanconi anemia-associated polypeptide of 16 kDa] |
Gene, Accession # | [CENPS], Gene ID: 378708, NCBI: NP_001257446.1, UniProt: Q8N2Z9 |
Catalog # | MBS9708708 |
Price | $130, $220, $325 |
Order / More Info | CENPS Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |