Vav (Phospho Tyr174) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Vav (Phospho Tyr174) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | immunogen affinity purified |
| Size | 0.03 mL, 0.1 mL, 0.2 mL |
| Concentration | 1 mg/ml |
| Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin, ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: Phospho-Vav (Y174) Polyclonal Antibody detects endogenous levels of Vav protein only when phosphorylated at Y174. VAV1 (vav guanine nucleotide exchange factor 1) is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. The encoded protein is important in hematopoiesis, playing a role in T-cell and B-cell development and activation. The encoded protein has been identified as the specific binding partner of Nef proteins from HIV-1. Coexpression and binding of these partners initiates profound morphological changes, cytoskeletal rearrangements and the JNK/SAPK signal |
| Immunogen | Immunogen: Synthesized peptide derived from human Vav around the phosphorylation site of Y174 |
| Other Names | [Rabbit Vav (phospho Tyr174); VAV1; Proto-oncogene vav] |
| Gene, Accession # | [VAV], Gene ID: 7409, NCBI: NP_005419.2, UniProt: P15498 |
| Catalog # | MBS9707109 |
| Price | $130, $220, $325 |
| Order / More Info | Vav (Phospho Tyr174) Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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