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Antigenic Specificity | FGFR1 (Ab-766) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total FGFR1 protein. Tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of embryonic development, cell proliferation, differentiation and migration. Required for normal mesoderm patterning and correct axial organization during embryonic development, normal skeletogenesis and normal development of the gonadotropin-releasing hormone (GnRH) neuronal system. Phosphorylates PLCG1, FRS2, GAB1 and SHB. Ligand binding leads to the activation of several signaling cascades. Activation of PLCG1 leads to the production of the cellular signaling molecules diacylglycerol and inositol 1,4,5-trisphosphate. Phosphorylation of FRS2 tr |
Immunogen | Immunogen Type: Peptide Immunogen Description: Synthesized non-phosphopeptide derived from human FGFR1 around the phosphorylation site of tyrosine 766 (Q-E-Y(p)-L-D). |
Other Names | [EC 2.7.10.1; FGFBR; FGFR-1; FGR1; FLG] |
Gene, Accession # | [FGFR1], Gene ID: 2260, NCBI: NP_001167534.1, UniProt: P11362 |
Catalog # | MBS9413936 |
Price | $200, $255 |
Order / More Info | FGFR1 (Ab-766) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |