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Antigenic Specificity | Human CD14 |
Clone | [26ic] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2b,k |
Format | Protein A purified |
Size | 0.1 mg, 0.5 mg |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: CD14, Cluster of differentiation 14, ingle-copy gene encoding 2 protein forms: a 50- to 55-kD glycosylphosphatidylinositol-anchored membrane protein(mCD14) and a monocyte or liver-derived soluble serum protein(sCD14) that lacks the anchor. By in situ hybridization and study of somatic cell hybrid DNA that the gene is located at bands 5q23-q31. CD14 acts as a co-receptor(along with the Toll-like receptor TLR 4 and MD-2) for the detection of bacterial lipopolysaccharide(LPS). CD14 can bind LPS only in the presence of lipopolysaccharide-binding protein(LBP). Although LPS is considered its main ligand, CD14 also recognizes other pathogen-associated molecular patterns. Protein Function: Coreceptor for bacterial lipopolysaccharide (P |
Immunogen | n/a |
Other Names | [Monocyte differentiation antigen CD14; Myeloid cell-specific leucine-rich glycoprotein; CD14; Monocyte differentiation antigen CD14, urinary form; Monocyte differentiation antigen CD14, membrane-bound form; CD14], [CD14; CD14] |
Gene, Accession # | [CD14], Gene ID: 929, NCBI: NP_000582.1, UniProt: P08571 |
Catalog # | MBS178868 |
Price | $145, $385 |
Order / More Info | Human CD14 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |