Nanog Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityNanog
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatepitope affinity purified
Size0.1 mg
Concentrationn/a
ApplicationsELISA (EIA), Flow Cytometry (FC/FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB)
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DescriptionThis antibody reacts with human Nanog. The other species are not tested. Embryonic stem (ES) cells derived from the inner cell mass (ICM) of blastocysts grow infinitely while maintaining pluripotency. Leukemia inhibitory factor (LIF) can maintain self-renewal of mouse ES cells through activation of Stat3. However, LIF/Stat3 is dispensable for maintenance of ICM and human ES cells, suggesting that the pathway is not fundamental for pluripotency. Nanog is a homeodomain containing transcription factor that is essential for the maintenance of pluripotency and self renewal in embryonic stem cells and ICM. Nanog expression is controlled by a network of factors including Sox2 and the key pluripotency regulator Oct4 and other transcription factors
Immunogenn/a
Other Names[Nanog homeobox], [NANOG; NANOG; hNanog]
Gene, Accession #Gene ID: 79923, NCBI: AFP91056.1
Catalog #MBS460513
Price$285
Order / More InfoNanog Antibody from MYBIOSOURCE INC.
Product Specific ReferencesMitsui, K., Tokuzawa, Y., Itoh, H., Segawa, K., Murakami, M., Takahashi, K., Maruyama, M., Maeda, M. and Yamanaka, S. The homeoprotein Nanog is required for maintenance of pluripotency in mouse epiblast and ES cells. Cell 113 (5), 631-642 (2003)
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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