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Antigenic Specificity | Chicken CD28 |
Clone | [AV7] |
Host Species | Mouse |
Reactive Species | chicken |
Isotype | IgG1 kappa |
Format | unconjugated |
Size | 0.5 mg |
Concentration | n/a |
Applications | Flow Cytometry; Immunoprecipitation |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Chicken CD28, a monomeric molecule of Mr 40-44 kDa with 50% amino acid sequence identity with mammalian CD28. Chicken CD28 antigen is a type I transmembrane monomeric glycoprotein which does not contain the cysteine residues that form disulfide-linked covalent homodimers found in the mammalian counterpart. This may reduce the avidity of binding to individual ligand molecules expected to be present on Ag presenting cells. Peripheral gamma delta + T cells are CD28-negative.1 Monoclonal antibodies against CD28 have a costimulatory effect on T cells stimulated by phorbol myristate acetate (PMA), concanavalin A or MAbs against the avian T cell receptor (TCR). Both V beta 1- and V beta 2-expressing cells respond equally well to stimu |
Immunogen | n/a |
Other Names | [Mouse Chicken CD28 - Purified, Unlabeled; Mouse Chicken CD28], [Cd28; Cd28] |
Gene, Accession # | Gene ID: 12487, UniProt: P31041 |
Catalog # | MBS673892 |
Price | $305 |
Order / More Info | Chicken CD28 Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Young, J.R., T.F. Davison, C.A. Tregaskes, M.C. Rennie, and O. Vainio. 1994. J. Immunol. 152:3848.2. Arstila, T.P., O. Vainio, and O. Lassila. 1994. Scand J. Immunol. 40:368. |