PD-L1 Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | PD-L1 |
| Clone | [IHC411] |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | IgG |
| Format | unconjugated |
| Size | 0.01 mL, 0.1 mL, 0.2 mL |
| Concentration | n/a |
| Applications | Immunohistochemistry (IHC) Paraffin |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | PD-L1 (Programmed Death-Ligand 1, CD274, B7-H1) is a transmembrane protein involved in suppressing the immune system. Tumor cells overexpressing PD-L1 could become resistant to CD8+ T-cell mediated lysis through binding to the PD-1 receptor, thus evading the host's immune system. In renal cell carcinoma, upregulation of PD-L1 has been linked to increased tumor aggressiveness and risk of death, and, in ovarian cancer, higher expression of this protein has led to significantly poorer prognosis. PD-L1 has also been linked to systemic lupus erythematosus and cutaneous melanoma. |
| Immunogen | n/a |
| Other Names | [programmed cell death 1 ligand 1 isoform c; Programmed cell death 1 ligand 1; programmed cell death 1 ligand 1; CD274 molecule; B7 homolog 1], [CD274; CD274; B7-H; B7H1; PDL1; PD-L1; PDCD1L1; PDCD1LG1; B7-H1] |
| Gene, Accession # | [PD-L1], Gene ID: 29126, NCBI: NP_001300958.1 |
| Catalog # | MBS346028 |
| Price | $170, $295, $435 |
| Order / More Info | PD-L1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
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