AAK1 (C-term), 790-819 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityAAK1 (C-term), 790-819
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman (predicted reactivity: bovine, mouse, porcine, rat)
Isotypen/a
Formatpurified
Size0.08 mL, 0.4 mL
Concentrationvial concentration: 2
ApplicationsWestern Blot (WB), ELISA (EIA)
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DescriptionThis AAK1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 790-819 amino acids from the C-terminal region of human AAK1. Adaptor-related protein complex 2 (AP-2 complexes) functions during receptor-mediated endocytosis to trigger clathrin assembly, interact with membrane-bound receptors, and recruit encodytic accessory factors. AAK1 is a member of the SNF1 subfamily of Ser/Thr protein kinases. The protein interacts with and phosphorylates a subunit of the AP-2 complex, which promotes binding of AP-2 to sorting signals found in membrane-bound receptors and subsequent receptor endocytosis. Its kinase activity is stimulated by clathrin.
Immunogenn/a
Other Names[AP2-associated protein kinase 1; Adaptor-associated kinase 1; AAK1; KIAA1048]
Gene, Accession #[AAK1], Gene ID: 22848, NCBI: NP_055726.3, UniProt: Q2M2I8
Catalog #MBS9200691
Price$165, $370
Order / More InfoAAK1 (C-term), 790-819 Antibody from MYBIOSOURCE INC.
Product Specific ReferencesHenderson,D.M., Mol. Biol. Cell 18 (7), 2698-2706 (2007) Takahashi,T., Cancer Res. 66 (24), 11932-11937 (2006) Schmid,E.M., PLoS Biol. 4 (9), E262 (2006)
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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