p53 Tumor Suppressor Protein Antibody from MYBIOSOURCE INC.

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Antigenic Specificityp53 Tumor Suppressor Protein
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, monkey, dog, mouse, rat, hamster
Isotypen/a
Formatpurified
Size0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml)
Concentrationn/a
ApplicationsELISA (EIA)
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DescriptionThe specificity of this monoclonal antibody to its intended target was validated by HuProtTM Array, containing more than 19,000, full-length human proteins. TP53/3156R binds to the C-terminus (aa370-378) of both wild type and mutated p53. When microinjected into nuclei, TP53/3156R blocked re-entry into the S-phase of the cell cycle. Mutation and/or allelic loss of p53 is one of the causes of a variety of mesenchymal and epithelial tumors. If it occurs in the germ line, such tumors run in families. p53 Binds to a DNA consensus sequence, the p53 response element, and it regulates normal cell growth cycle events by activating transcription of genes, involved either in progression through the cycle, or causing arrest in G1 when the genome is da
ImmunogenImmunogen: SV40-transformed Mouse B4 cells
Other Names[Antigen NY-CO-13; BCC7; Cellular Tumor Antigen p53; LFS1; TP53; Transformation Related Protein 53 (TRP53)]
Gene, Accession #[TP53], Gene ID: 7157, NCBI: NP_000537.3, UniProt: P04637
Catalog #MBS4381307
Price$190, $340, $340
Order / More Infop53 Tumor Suppressor Protein Antibody from MYBIOSOURCE INC.
Product Specific ReferencesGurney EG et. al. Journal of Virology, 1980, 34(3):752-63.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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