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Antigenic Specificity | DDX58 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: DDX58 antibody detects endogenous levels of total DDX58. Description: Antiviral innate immunity depends on the combination of parallel pathways triggered by virus detecting proteins in the Toll-like receptor (TLR) family and RNA helicases, such as Rig-I (retinoic acid-inducible gene I) and MDA-5 (melanoma differentiation-associated antigen 5), which promote the transcription of type I interferons (IFN) and antiviral enzymes (1-3). TLRs and helicase proteins contain sites that recognize the molecular patterns of different virus types, including DNA, single-stranded RNA (ssRNA), double-stranded RNA (dsRNA), and glycoproteins. These antiviral proteins are found in different cell compartments; TLRs (i.e. TLR3, TLR7, TLR8, and TLR9) |
Immunogen | Immunogen: A synthetic peptide of human DDX58 Subcellular Location: Cytoplasm. Colocalized with TRIM25 at cytoplasmic perinuclear bodies. Tissue Specificity: Present in vascular smooth cells (at protein level). Predicted Cross Reactivity: Pig, Bovine, Horse, Sheep, Rabbit, Dog Similarity: Pig (92%), Bovine (92%), Horse (92%), Sheep (100%), Rabbit (100%), Dog (92%) |
Other Names | [Ddx58; DDX58_HUMAN; DEAD (Asp Glu Ala Asp) box polypeptide 58; DEAD (Asp Glu Ala Asp/His) box polypeptide; DEAD box protein 58; DEAD/H (Asp Glu Ala Asp/His) box polypeptide RIG1; DKFZp434J1111; DKFZp686N19181; FLJ13599; Probable ATP dependent RNA helicase DDX58; Probable ATP-dependent RNA helicase DDX58; Retinoic acid inducible gene 1 protein; Retinoic acid-inducible gene 1 protein; Retinoic acid-inducible gene I protein; RIG I; Rig-1; RIG-I; RIG1; rigi; RLR 1; RNA helicase; RNA helicase RIG I; SGMRT2] |
Gene, Accession # | [DDX58], Gene ID: 23586, NCBI: NP_055129.2, UniProt: O95786 |
Catalog # | MBS9606768 |
Price | $240, $280 |
Order / More Info | DDX58 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |