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Antigenic Specificity | SHP1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 0.05 mg |
Concentration | 1 mg/ml |
Applications | Immunofluorescence (IF), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | SHP1 is an unusual orphan receptor that contains a putative ligand-binding domain but lacks a conventional DNA-binding domain. It is a member of the nuclear hormone receptor family, a group of transcription factors regulated by small hydrophobic hormones, a subset of which do not have known ligands and are referred to as orphan nuclear receptors. The protein has been shown to interact with retinoid and thyroid hormone receptors, inhibiting their ligand-dependent transcriptional activation. In addition, interaction with estrogen receptors has been demonstrated, leading to inhibition of function. |
Immunogen | Immunogen: SHP1 antibody was raised in Rabbit using the peptide sequence around phosphorylation site of tyrosine 536 (S-E-Y(p)-G-N) derived from Human SHP-1 as the immunogen. |
Other Names | [Rabbit SHP1; SHP1; SHP1; SHP 1; Phospho Tyr536; Nuclear Receptor Subfamily 0 Group B Member 2; SHP-1; SHP 1; SHP; SHP-1; SHP1; NR0B2] |
Gene, Accession # | [SHP1], NCBI: CAA84878.1, UniProt: P34223 |
Catalog # | MBS5309615 |
Price | $295 |
Order / More Info | SHP1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |