SHP1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificitySHP1
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatimmunoaffinity purified
Size0.05 mg
Concentration1 mg/ml
ApplicationsImmunofluorescence (IF), Immunohistochemistry (IHC)
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DescriptionSHP1 is an unusual orphan receptor that contains a putative ligand-binding domain but lacks a conventional DNA-binding domain. It is a member of the nuclear hormone receptor family, a group of transcription factors regulated by small hydrophobic hormones, a subset of which do not have known ligands and are referred to as orphan nuclear receptors. The protein has been shown to interact with retinoid and thyroid hormone receptors, inhibiting their ligand-dependent transcriptional activation. In addition, interaction with estrogen receptors has been demonstrated, leading to inhibition of function.
ImmunogenImmunogen: SHP1 antibody was raised in Rabbit using the peptide sequence around phosphorylation site of tyrosine 536 (S-E-Y(p)-G-N) derived from Human SHP-1 as the immunogen.
Other Names[Rabbit SHP1; SHP1; SHP1; SHP 1; Phospho Tyr536; Nuclear Receptor Subfamily 0 Group B Member 2; SHP-1; SHP 1; SHP; SHP-1; SHP1; NR0B2]
Gene, Accession #[SHP1], NCBI: CAA84878.1, UniProt: P34223
Catalog #MBS5309615
Price$295
Order / More InfoSHP1 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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