Edit |   |
---|---|
Antigenic Specificity | HDAC6 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemisty (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: HDAC6 antibody detects endogenous levels of total HDAC6. Description: HDAC6 is a class II histone deacetylase enzyme localized to the cytoplasm and associated with the microtubule network (1). It is involved in the regulation of many cellular processes, including cell migration, immune synapse formation, viral infection, and degradation of misfolded proteins (1). HDAC6 contains two tandem catalytic domains that facilitate the deacetylation of multiple protein substrates, including histones and non-histone proteins such as tubulin, cortactin, and HSP90. Despite the ability to deacetylate histone proteins in vitro, there is no evidence for HDAC6-mediated deacetylation of histones in vivo (2, 3). The acetylation/deacetylation of t |
Immunogen | Immunogen: A synthesized peptide derived from human HDAC6 Subcellular Location: Nucleus. Cytoplasm. It is mainly cytoplasmic, where it is associated with microtubules. |
Other Names | [CPBHM; FLJ16239; HD 6; HD6; HDAC 6; HDAC6; HDAC6_HUMAN; Histone deacetylase 6 (HD6); Histone deacetylase 6; JM 21; JM21; KIAA0901; OTTHUMP00000032398; OTTHUMP00000197663; PPP1R90; Protein phosphatase 1 regulatory subunit 90] |
Gene, Accession # | [HDAC6], Gene ID: 10013, NCBI: NP_001308155.1, UniProt: Q9UBN7 |
Catalog # | MBS9607238 |
Price | $240, $280 |
Order / More Info | HDAC6 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |