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Antigenic Specificity | SGLT2/SLC5A2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin, Direct ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: No cross reactivity with other proteins. Description: Rabbit IgG polyclonal antibody for SGLT2/SLC5A2 detection. Tested with WB, IHC-P, Direct ELISA in Human; Mouse; Rat.Background: The sodium/glucose cotransporter 2 (SGLT2) is a protein that in humans is encoded by the SLC5A2 gene. It is mapped to 16p11.2. This gene encodes a member of the sodium glucose cotransporter family which are sodium-dependent glucose transport proteins. The encoded protein is the major cotransporter involved in glucose reabsorption in the kidney. Mutations in this gene are associated with renal glucosuria. Two transcript variants, one protein-coding and one not, have been found for this gene. |
Immunogen | Immunogen: E Coli-derived human SGLT2/SLC5A2 recombinant protein (Position: A15-N656). Contents: Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3. Relevant Detection Systems: Relevant Detection Systems: We recommend Enhanced Chemiluminescent Kit with anti-Rabbit IgG (MBS176460) for Western blot, and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (MBS176453) for IHC(P). |
Other Names | [Sodium/glucose cotransporter 2; solute carrier family 5 member 2; Sodium/glucose cotransporter 2; Na(+)/glucose cotransporter 2; Low affinity sodium-glucose cotransporter; Solute carrier family 5 member 2; SLC5A2; SGLT2] |
Gene, Accession # | [SGLT2/SLC5A2], Gene ID: 6524, NCBI: NP_003032.1, UniProt: P31639 |
Catalog # | MBS1752504 |
Price | $315 |
Order / More Info | SGLT2/SLC5A2 Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Calado, J., Soto, K., Clemente, C., Correia, P., Rueff, J. Novel compound heterozygous mutations in SLC5A2 are responsible for autosomal recessive renal glucosuria. Hum. Genet. 114: 314-316, 2004. 2. Wells, R. G., Pajor, A. M., Kanai, Y., Turk, E., Wright, E. M., Hediger, M. A. Cloning of a human kidney cDNA with similarity to the sodium-glucose cotransporter. Am. J. Physiol. 263: F459-F465, 1992. |