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Antigenic Specificity | Caspase-6 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunoprecipitation (IP) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Caspase-6 (Mch2) is one of the major executioner caspases functioning in cellular apoptotic processes. Upon apoptotic stimulation, initiator caspases such as caspase-9 are cleaved and activated. The activated upstream caspases further process downstream executioner caspases, such as caspase-3 and caspase-6, by cleaving them into large and small subunits, thereby initiating a caspase cascade leading to apoptosis. One of the major targets for caspase-6 is the membrane associated protein lamin A. |
Immunogen | Immunogen: A synthesized peptide derived from human Caspase-6 |
Other Names | [MCH2; Caspase-6] |
Gene, Accession # | [CASP6], Gene ID: 839, NCBI: NP_001217.2, UniProt: P55212 |
Catalog # | MBS8542629 |
Price | $280 |
Order / More Info | Caspase-6 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |