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Antigenic Specificity | MHC Class I (H-2K) |
Clone | [NYRmH-2K] |
Host Species | Mouse |
Reactive Species | n/a |
Isotype | IgG2b |
Format | ion exchange purified |
Size | 0.5 mg, 1 mg |
Concentration | 1mg/ml in PBS (after reconstitution). |
Applications | n/a |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Recognizes most mouse H-2K haplotypes (k,p,q,r,s). Does NOT react with H-2kd. Introduction: MHC Class I is a membrane spanning molecule consisting of 2 proteins. MHC Class I is just about 350 amino acids in length, with roughly 75 amino acids at the carboxylic end comprising the transmembrane and cytoplasmic portions. The remaining 270 amino acids, are divided into three globular domains labeled Alpha-1, Alpha-2 and Alpha-3 prime, with Alpha-1 being closest to the amino terminus and Alpha-3 closest to the membrane. The second portion of the molecule is a small globular protein called Beta-2 Microglobulin It links primarily with the Alpha-3 prime domain and is essential for MHC stability. The MHC ability to show a vast range of antigenic pep |
Immunogen | Immunogen: Purified mouse LN cells (C57Bl/6 anti-BALB/c). Antibody Properties: Cytotoxic and staining antibody. For staining, use 10ml/1,000,000 cells. Titer for cytotoxicity should be determined by the investigator. |
Other Names | [MHC Class I, H-2K; MHC Class I, (H-2K) Mouse], [gamr-UA-c24] |
Gene, Accession # | [MHC Class I], NCBI: O98279 |
Catalog # | MBS140072 |
Price | $305, $455 |
Order / More Info | MHC Class I (H-2K) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |