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Antigenic Specificity | p53 |
Clone | polyclonal |
Host Species | Sheep |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | ammonium sulfate precipitate |
Size | 0.25 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | GST p53 fusion protein containing amino acids 1-393 of human p53was used as immunogen. p53 has a molecular weight of 53kDa p53 is a transcription factor that can inhibit cell cycle progression or induce apoptosis in response to stress or DNA damage. Disruption of the p53 signalling pathway through various mechanisms is the most common alteration in human cancer occuring in over half of all tumors. The p53 protein is short lived and expressed at low levels in normal cells but accumulates and/or is activated in cells that have undergone genotoxic damage or oncogene activation. Many tumor derived and transformed cell lines express elevated levels of mutant p53 protein. |
Immunogen | Immunogen: GST p53 fusion protein containing amino acids 1-393 of human p53 |
Other Names | [Sheep human p53; hp53], [TP53; TP53; P53; BCC7; LFS1; TRP53; P53] |
Gene, Accession # | [p53], Gene ID: 7157, NCBI: NP_000537.3, UniProt: P04637 |
Catalog # | MBS395752 |
Price | $340 |
Order / More Info | p53 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |