MRGPRX2 (C-term), 287-315 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | MRGPRX2 (C-term), 287-315 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 0.5 |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This MRGPRX2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 287-315 amino acids from the C-terminal region of human MRGPRX2. MRGPRX2 is the orphan receptor. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and/or development, including the sensation or modulation of pain. Cortistatin-14 seems to be a high potency ligand at this receptor. Cortistatin has several biological functions including roles in sleep regulation locomotor activity, and cortical function. In receptor-expressing cells, cortistatin-stimulated increases in intracellular Ca(2+) but had no effect on basal or forskolin-stimulated cAMP levels, suggesting that this receptor is G(q)-coupled. |
| Immunogen | n/a |
| Other Names | [Mas-related G-protein coupled receptor member X2; MRGPRX2; MRGX2] |
| Gene, Accession # | [MRGPRX2], Gene ID: 117194, NCBI: NP_473371.1, UniProt: Q96LB1 |
| Catalog # | MBS9213308 |
| Price | $165, $370 |
| Order / More Info | MRGPRX2 (C-term), 287-315 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Gembardt, F., et al. Mol. Cell. Biochem. 319 (1-2), 115-123 (2008) : Yang, S., et al. Gene 352, 30-35 (2005) : Robas, N., et al. J. Biol. Chem. 278(45):44400-44404(2003) Takeda, S., et al. FEBS Lett. 520 (1-3), 97-101 (2002) : Dong, X., et al. Cell 106(5):619-632(2001) |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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