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Antigenic Specificity | RB1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.02 mL, 0.06 mL, 0.12 mL |
Concentration | 2.1mg/mL |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma |
Immunogen | Immunogen: Recombinant protein of human RB1 Calculated Molecular Weight: 106kDa |
Other Names | [RB; pRb; OSRC; pp110; p105-Rb] |
Gene, Accession # | [RB1], Gene ID: 5925, NCBI: NP_000312.2 |
Catalog # | MBS2517413 |
Price | $110, $150, $225 |
Order / More Info | RB1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |