ERLIN1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityERLIN1
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, ratpredicted: porcine, horse, rabbit, dog
Isotypen/a
Formatpeptide affinity purified
Size0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB)
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DescriptionSpecificity: ERLIN1 Antibody detects endogenous levels of ERLIN1. Description: Component of the ERLIN1/ERLIN2 complex which mediates the endoplasmic reticulum-associated degradation (ERAD) of inositol 1,4,5-trisphosphate receptors (IP3Rs). Involved in regulation of cellular cholesterol homeostasis by regulation the SREBP signaling pathway. Binds cholesterol and may promote ER retention of the SCAP-SREBF complex (PubMed:24217618).Subunit Structure: Forms a heteromeric complex with ERLIN2 (PubMed:19240031). In complex with ERLIN2, interacts with RNF170 (PubMed:21610068). Interacts with AMFR and SYVN1 (PubMed:21343306).Similarity: Belongs to the band 7/mec-2 family.
ImmunogenImmunogen: A synthesized peptide derived from human ERLIN1. Tissue Specificity: Expressed in heart, placenta, liver, kidney, pancreas, prostate, testis, ovary and small intestine.
Other Names[Band 7 23-211 Keo4 (Interim) similar to C.elegans protein; C10orf69; chromosome 10 open reading frame 69; Endoplasmic reticulum lipid raft-associated protein 1; ER lipid raft associated 1; Erlin 1; Erlin-1; ERLIN1; ERLN1_HUMAN; KE04; KEO4; OTTHUMP00000059425; Protein KE04; SPFH domain containing protein 1; SPFH domain family, member 1; SPFH domain-containing protein 1; SPFH1; SPG62; Stomatin-prohibitin-flotillin-HflC/K domain containing protein 1; Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 1]
Gene, Accession #[ERLIN1], Gene ID: 10613, NCBI: NP_001094096, UniProt: O75477
Catalog #MBS9611734
Price$240, $280
Order / More InfoERLIN1 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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