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Antigenic Specificity | Irf8 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peroxidase (HRP) conjugate |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specifically binds to the upstream regulatory region of type I IFN and IFN-inducible MHC class I genes (the interferon consensus sequence (ICS)). Plays a regulatory role in cells of the immune system. Involved in CD8+ dendritic cell differentiation by forming a complex with the BATF-JUNB heterodimer in immune cells, leading to recognition of AICE sequence (5'-TGAnTCA/GAAA-3'), an immune-specific regulatory element, followed by cooperative binding of BATF and IRF8 and activation of genes. |
Immunogen | Immunogen: Recombinant human Interferon regulatory factor 8 protein(1-424AA) Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-32527 / sc-32528 |
Other Names | [Interferon regulatory factor 8; IRF-8; Interferon consensus sequence-binding protein; ICSBP; Irf8; Icsbp; Icsbp1], [Irf8; Irf8; Myls; ICSBP; IRF-8; Icsbp1; AI893568; Icsbp; Icsbp1; IRF-8; ICSBP] |
Gene, Accession # | [Irf8], Gene ID: 15900, NCBI: NP_001288740.1, UniProt: P23611 |
Catalog # | MBS1492998 |
Price | $160, $235 |
Order / More Info | Irf8 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |