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Antigenic Specificity | AKT2 (Phospho Ser474) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin, ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Phospho-Akt2 (S474) Polyclonal Antibody detects endogenous levels of Akt2 protein only when phosphorylated at S474. AKT2 is a putative oncogene encoding a protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains. AKT2 was shown to be amplified and overexpressed in 2 of 8 ovarian carcinoma cell lines and 2 of 15 primary ovarian tumors. Overexpression contributes to the malignant phenotype of a subset of human ductal pancreatic cancers. AKT serine/threonine kinase 2 is a general protein kinase capable of phophorylating several known proteins. |
Immunogen | Immunogen: Synthesized peptide derived from human Akt2 around the phosphorylation site of S474 |
Other Names | [Rabbit Akt2 (phospho Ser474); AKT2; RAC-beta serine/threonine-protein kinase; Protein kinase Akt-2; Protein kinase B beta; PKB beta; RAC-PK-beta] |
Gene, Accession # | [AKT2], Gene ID: 208, NCBI: NP_001617.1, UniProt: P31751 |
Catalog # | MBS9701022 |
Price | $130, $220, $325 |
Order / More Info | AKT2 (Phospho Ser474) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |