AKT2 (Phospho Ser474) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityAKT2 (Phospho Ser474)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatimmunogen affinity purified
Size0.03 mL, 0.1 mL, 0.2 mL
Concentration1 mg/ml
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC) Paraffin, ELISA (EIA)
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DescriptionSpecificity: Phospho-Akt2 (S474) Polyclonal Antibody detects endogenous levels of Akt2 protein only when phosphorylated at S474. AKT2 is a putative oncogene encoding a protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains. AKT2 was shown to be amplified and overexpressed in 2 of 8 ovarian carcinoma cell lines and 2 of 15 primary ovarian tumors. Overexpression contributes to the malignant phenotype of a subset of human ductal pancreatic cancers. AKT serine/threonine kinase 2 is a general protein kinase capable of phophorylating several known proteins.
ImmunogenImmunogen: Synthesized peptide derived from human Akt2 around the phosphorylation site of S474
Other Names[Rabbit Akt2 (phospho Ser474); AKT2; RAC-beta serine/threonine-protein kinase; Protein kinase Akt-2; Protein kinase B beta; PKB beta; RAC-PK-beta]
Gene, Accession #[AKT2], Gene ID: 208, NCBI: NP_001617.1, UniProt: P31751
Catalog #MBS9701022
Price$130, $220, $325
Order / More InfoAKT2 (Phospho Ser474) Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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