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Antigenic Specificity | RORA |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Nuclear receptor that binds DNA as a monomer to ROR response elements (RORE) containing a single core motif half-site 5'-AGGTCA-3' preceded by a short A-T-rich sequence. Key regulator of embryonic development, cellular differentiation, immunity, circadian rhythm as well as lipid, steroid, xenobiotics and glucose metabolism. Considered to have intrinsic transcriptional activity, have some natural ligands like oxysterols that act as agonists (25-hydroxycholesterol) or inverse agonists (7-oxygenated sterols), enhancing or repressing the transcriptional activity, respectively. Recruits distinct combinations of cofactors to target genes regulatory regions to modulate their transcriptional expression, depending on the tissue, time and promoter co |
Immunogen | Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 169-468 of human RORA (NP 599024.1). |
Other Names | [ROR1; ROR2; ROR3; RZRA; NR1F1; IDDECA; RZR-ALPHA] |
Gene, Accession # | [RORA], Gene ID: 6095, NCBI: NP_002934.1, UniProt: P35398 |
Catalog # | MBS8546478 |
Price | $280 |
Order / More Info | RORA Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |