HDAC8 (Phospho-Ser39) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHDAC8 (Phospho-Ser39)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatepitope affinity purified
Size0.05 mL, 0.1 mL
Concentration1.0 mg/ml
ApplicationsImmunohistochemistry (IHC), Immunofluorescence (IF)
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DescriptionThe antibody detects endogenous level of HDAC8 only when phosphorylated at serine 39. Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by HDAC8 gene belongs to class I of the histone deacetylase family. It catalyzes the deacetylation of lysine residues in the histone N-terminal tails and represses transcription in large multiprotein complexes with transcriptional co-repressors. Multiple transcript variants encoding different isoforms have been found for this gene.
ImmunogenImmunogen Type: Peptide-KLH Immunogen Description: Peptide sequence around phosphorylation site of serine 39 (R-A-S(p)-M-V) derived from Human HDAC8.
Other Names[HD8; HDA8; HDACL1]
Gene, Accession #[HDAC8], Gene ID: 55869, NCBI: NP_001159890.1, UniProt: Q9BY41
Catalog #MBS9400985
Price$200, $255
Order / More InfoHDAC8 (Phospho-Ser39) Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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