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Antigenic Specificity | MAP3K8 - C-terminal region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | cow, dog, guinea pig, horse, human, mouse, rabbit, rat |
Isotype | n/a |
Format | Protein A purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This is a rabbit polyclonal antibody against MAP3K8. It was validated on Western Blot using a cell lysate as a positive control.Target Description: MAP3K8 is a member of the serine/threonine protein kinase family. This kinase can activate both the MAP kinase and JNK kinase pathways. This kinase was shown to activate IkappaB kinases, and thus induce the nuclear production of NF-kappaB. This kinase was also found to promote the production of TNF-alpha and IL-2 during T lymphocyte activation. Studies of a similar gene in rat suggested the direct involvement of this kinase in the proteolysis of NF-kappaB1,p105 (NFKB1). This gene may also utilize a downstream in-frame translation start codon, and thus produce an isoform containing a shor |
Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human MAP3K8 |
Other Names | [mitogen-activated protein kinase kinase kinase 8; Mitogen-activated protein kinase kinase kinase 8; mitogen-activated protein kinase kinase kinase 8; mitogen-activated protein kinase kinase kinase 8; Cancer Osaka thyroid oncogene; Proto-oncogene c-Cot; Serine/threonine-protein kinase cot; Tumor progression locus 2] |
Gene, Accession # | [MAP3K8], Gene ID: 1326, NCBI: NP_005195, UniProt: P41279 |
Catalog # | MBS3200271 |
Price | $270 |
Order / More Info | MAP3K8 - C-terminal region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |