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Antigenic Specificity | ARA54 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: ARA54 Polyclonal Antibody detects endogenous levels of ARA54 protein. The protein encoded by RNF14 (ring finger protein 14) contains a RING zinc finger, a motif known to be involved in protein-protein interactions. This protein interacts with androgen receptor (AR) and may function as a coactivator that induces AR target gene expression in prostate. A dominant negative mutant of RNF14 has been demonstrated to inhibit the AR-mediated growth of prostate cancer. This protein also interacts with class III ubiquitin-conjugating enzymes (E2s) and may act as a ubiquitin-ligase (E3) in the ubiquitination of certain nuclear proteins. Six alternatively spliced transcript variants encoding two distinct isoforms have been reported. |
Immunogen | Immunogen: Synthesized peptide derived from the C-terminal region of human ARA54 at AA range: 330-410 |
Other Names | [Rabbit ARA54; RNF14; ARA54; HRIHFB2038; E3 ubiquitin-protein ligase RNF14; Androgen receptor-associated protein 54; HFB30; RING finger protein 14; Triad2 protein] |
Gene, Accession # | [ARA54], Gene ID: 9604, NCBI: NP_001188294.1, UniProt: Q9UBS8 |
Catalog # | MBS9707692 |
Price | $130, $220, $325 |
Order / More Info | ARA54 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |