HSP27 Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | HSP27 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | n/a |
| Applications | Western Blot (WB), Immunofluorescence (IF) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Rabbit polyclonal to HSP27. Heat shock protein (HSP) 27 is one of the small HSPs that are constitutively expressed at different levels in various cell types and tissues. Like other small heat shock proteins, HSP27 is regulated at both the transcriptional and posttranslational levels (1). In response to stress, the expression level of HSP27 increases several-fold to confer cellular resistance to the adverse environmental change. HSP27 is phosphorylated at Ser15, Ser78 and Ser82 by MAPKAP kinase 2 as a result of the activation of the p38 MAP kinase pathway (2,3). Phosphorylation of HSP27 causes a change in its tertiary structure, which shifts from large homotypic multimers to dimers and monomers (4). It has been shown that phosphorylation and |
| Immunogen | Immunogen: A synthetic -peptide of human HSP27 |
| Other Names | [HSPB1; HSP27; HSP27; HSPB1; CMT2F; DKFZp586P1322; HMN2B; HS.76067; HSP27; HSP28; Hsp25; SRP27], [HSPB1; HSPB1; CMT2F; HMN2B; HSP27; HSP28; Hsp25; SRP27; HS.76067; HSP27; HSP28; HspB1; HSP 27; SRP27] |
| Gene, Accession # | Gene ID: 3315, NCBI: NP_001531.1, UniProt: P04792 |
| Catalog # | MBS126032 |
| Price | $275, $430 |
| Order / More Info | HSP27 Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Arrigo, A.P. and Landry, J. (1994) Cold Spring Harbor Laboratory Press, NY, 335-373. 2. Landry, J. et al. (1992) J. Biol. Chem. 267, 794-803. 3. Rouse, J. et al. (1994) Cell 78, 1027-1037. 4. Rogalla, T. et al. (1999) J. Biol. Chem. 274, 18947-18956. 5. Lavoie, J. et al. (1993) J. Biol. Chem. 268, 24210-24214. 6. Rousseau, S. et al. (1997) Oncogene 15, 2169-2177. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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