Human CHRM2 / M2 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Human CHRM2 / M2 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | Bat, Gibbon, bovine, chimpanzee, dog, guinea pig, gorilla, hamster, human, monkey, mouse, orangutan, porcine, rabbit, rat, sheep |
| Isotype | n/a |
| Format | immunoaffinity purified |
| Size | 0.05 mg |
| Concentration | 1 mg/ml |
| Applications | Immunohistochemistry (IHC - Paraffin) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: Human CHRM2. BLAST analysis of the peptide immunogen showed no homology with other human proteins. Muscarinic cholinergic receptor 2, an Acetylcholine Receptor, has been suggested to function as a presynaptic autoreceptor that inhibits acetylcholine release. The M2 receptor has also been suggested to mediate smooth muscle contractility. Alzheimer's disease (AD) involves selective loss of M2 subtype receptors in cortical and hippocampal regions of the human brain. Increase in M2 receptor heterozygosity has been associated with depression in women. |
| Immunogen | Immunogen Description: Synthetic 16 amino acid peptide from 3rd cytoplasmic domain of human CHRM2. Percent identity with other species by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Gibbon, Monkey, Marmoset, Mouse, Rat, Sheep, Dog, Bat, Bovine, Hamster, Panda. |
| Other Names | [CHRM2 / M2 (Cytoplasmic Domain) IHC-plus; CHRM2; 7TM receptor; HM2; M2 muscarinic receptor; M2-mAChR; Muscarinic receptor M2; Muscarinic M2 receptor; Human CHRM2; M2], [CHRM2; CHRM2; HM2] |
| Gene, Accession # | [CHRM2], Gene ID: 1129, NCBI: NP_000730.1, UniProt: P08172 |
| Catalog # | MBS244587 |
| Price | $530 |
| Order / More Info | Human CHRM2 / M2 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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