PPP4C - middle region Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | PPP4C - middle region |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Protein phosphatase that is involved in many processes such as microtubule organization at centrosomes, maturation of spliceosomal snRNPs, apoptosis, DNA repair, tumor necrosis factor (TNF)-alpha signaling, activation of c-Jun N-terminal kinase MAPK8, regulation of histone acetylation, DNA damage checkpoint signaling, NF-kappa-B activation and cell migration. The PPP4C-PPP4R1 PP4 complex may play a role in dephosphorylation and regulation of HDAC3. The PPP4C-PPP4R2-PPP4R3A PP4 complex specifically dephosphorylates H2AFX phosphorylated on Ser-140 (gamma-H2AFX) generated during DNA replication and required for DNA double strand break repair. Dephosphorylates NDEL1 at CDK1 phosphorylation sites and negatively regulates CDK1 activity in interph |
| Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human PPP4C |
| Other Names | [serine/threonine-protein phosphatase 4 catalytic subunit isoform 1; Serine/threonine-protein phosphatase 4 catalytic subunit; serine/threonine-protein phosphatase 4 catalytic subunit; protein phosphatase 4 catalytic subunit; Protein phosphatase X; PP-X] |
| Gene, Accession # | [PPP4C], Gene ID: 5531, NCBI: NP_002711.1, UniProt: P60510 |
| Catalog # | MBS3222045 |
| Price | $335 |
| Order / More Info | PPP4C - middle region Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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