Calcineurin B homologous protein 2/HCC Antigen 520 Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-Calcineurin B homologous protein 2/HCC Antigen 520 antibody, protein, ELISA kits.
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| Antigenic Specificity | Calcineurin B homologous protein 2/HCC Antigen 520 |
| Clone | [CPTC-CHP2-1] |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG2c, kappa |
| Format | purified |
| Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml) |
| Concentration | n/a |
| Applications | Western Blot (WB), Immunofluorescence (IF) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: CHP2 (calcineurin B homologous protein 2), also known as hepatocellular carcinoma-associated antigen 520, is a 196 amino acid protein that contains 4 EF-hand domains and plays a potential role in transmembrane Na+/H+ exchange. By binding to and activating NHE-1, CHP2 increases the pH and works to protect cells from serum deprivation-induced death. Though not typically detected in normal tissues, CHP2 is highly expressed in malignantly transformed cells and is therefore considered to be a tumor-associated antigen. Ectopic expression of CHP2 promotes proliferation of HEK293 cells and knockdown of CHP2 mRNA in HepG2 cells inhibits cell proliferation. Like calcineurin B, CHP2 can bind to and stimulate phosphatase activity of calcin |
| Immunogen | Immunogen: Recombinant human full-length CHP2 protein |
| Other Names | [calcineurin-like EF hand protein 2; calcineurin-like EF-hand protein 2; HCA520; hepatocellular carcinoma antigen gene 520; Hepatocellular carcinoma-associated antigen 520 homolog] |
| Gene, Accession # | [CHP2], Gene ID: 63928, NCBI: NP_071380.1, UniProt: O43745 |
| Catalog # | MBS4381241 |
| Price | $190, $340, $340 |
| Order / More Info | Calcineurin B homologous protein 2/HCC Antigen 520 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Ammar, YB. et al. The EMBO Journal, EMBO Press, 7 June 2006. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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