Huntingtin (Phospho Ser421) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Huntingtin (Phospho Ser421) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | immunogen affinity purified |
| Size | 0.03 mL, 0.1 mL, 0.2 mL |
| Concentration | 1 mg/ml |
| Applications | Immunohistochemistry (IHC) Paraffin, ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: Phospho-Huntingtin (S421) Polyclonal Antibody detects endogenous levels of Huntingtin protein only when phosphorylated at S421. Huntingtin is a disease gene linked to Huntington's disease, a neurodegenerative disorder characterized by loss of striatal neurons. This is thought to be caused by an expanded, unstable trinucleotide repeat in the huntingtin gene, which translates as a polyglutamine repeat in the protein product. A fairly broad range of trinucleotide repeats (9-35) has been identified in normal controls, and repeat numbers in excess of 40 have been described as pathological. The huntingtin locus is large, spanning 180 kb and consisting of 67 exons. The huntingtin gene is widely expressed and is required for normal dev |
| Immunogen | Immunogen: Synthesized peptide derived from human Huntingtin around the phosphorylation site of S421 |
| Other Names | [Rabbit Huntingtin (phospho Ser421); HD; IT15; Huntingtin; Huntington disease protein; HD protein] |
| Gene, Accession # | [HTT], Gene ID: 3064, NCBI: NP_002102.4, UniProt: P42858 |
| Catalog # | MBS9705367 |
| Price | $130, $220, $325 |
| Order / More Info | Huntingtin (Phospho Ser421) Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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