DCC Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityDCC
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatimmunogen affinity purified
Size0.05 mL, 0.1 mL
Concentration1.0 mg/ml
ApplicationsImmunofluorescence (IF)
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DescriptionThe antibody detects endogenous levels of total DCC protein. Receptor for netrin required for axon guidance. Mediates axon attraction of neuronal growth cones in the developing nervous system upon ligand binding. Its association with UNC5 proteins may trigger signaling for axon repulsion. It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand. Implicated as a tumor suppressor gene.Hedrick L., Genes Dev. 8:1174-1183(1994).Cho K.R., Genomics 19:525-531(1994).Sjoeblom T., Science 314:268-274(2006).
ImmunogenImmunogen Type: Peptide Immunogen Description: Synthesized peptide derived from internal of human DCC.
Other Names[colorectal cancer suppressor; deleted in colorectal carcinoma; netrin receptor DCC; tumor suppressor protein DCC]
Gene, Accession #[DCC], Gene ID: 1630, NCBI: NP_005206.2, UniProt: P43146
Catalog #MBS9405453
Price$200, $255
Order / More InfoDCC Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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