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Antigenic Specificity | p44 / 42 MAPK (Erk1 / 2) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat, sheep, chicken |
Isotype | n/a |
Format | affinity purified |
Size | 0.03 mg, 0.1 mg |
Concentration | 0.5 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Background: The extracellular signal-regulated kinase 1 and 2 (Erk1 and Erk2) are closely related mitogen activated protein (MAP) kinases that are activated thromugh the extracellular stimulation by many growth factors, mitogens and differentiation promoting agents via a protein kinase cascade. Erk1/2 are activated approximately 1000 fold by phosphorylation of neighboring threonine and tyrosine residues by Mek1 and Mek2. Both sites must be phosphorylated for maximum activity. Erk1/2 kinases are ubiquitously distributed in the nervous system, as well as a broad range of cells and tissues. These two kinases represent proximal kinases in the classical MAP kinase cascade pathway which links growth and differentiation signals at the cell surface |
Immunogen | Immunogen: Synthetic peptide surrounding amino acid 340 of rat ERK2/MAPK1. Positive Control: Mouses 3T3 cell lysate, Jurkat cell lysate, rat kidney tissue lysate |
Other Names | [MAPK1; p38; ERK; P42MAPK; ERK2; p40; PRKM1; p41mapk; PRKM2; MAPK2; p42-MAPK; p41; ERK-2; ERT1], [Mapk1; Mapk1; ERT1; Erk2; ERK-2; p42-MAPK; Erk2; Mapk; Prkm1; MAP kinase 1; MAPK 1; ERK-2; p42-MAPK; MAP kinase 2; MAPK 2] |
Gene, Accession # | Gene ID: 116590, NCBI: NP_446294.1, UniProt: P63086 |
Catalog # | MBS840401 |
Price | $150, $300 |
Order / More Info | p44 / 42 MAPK (Erk1 / 2) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |