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Antigenic Specificity | VASP (pSer157) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.05 mL |
Concentration | n/a |
Applications | Immunoprecipitation (IP), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti VASP (pSer157) antibody recognizes vasodilator-stimulated phosphoprotein (VASP), when phosphorylated at serine 157. VASP belongs to the Ena/VASP family and is associated with actin filaments and focal adhesions. It is involved in the remodeling of the actin cytoskeleton and platelet aggregation (Machesky, L.M. 2000, Krause, M. et al. 2003 & Aszodi, A. et al. 1999). In platelets VASP is phosphorylated on serine 157 by PKC and Rho kinases in response to thrombin (Wentworth, J.K. et al. 2006). Phosphorylation of VASP regulates its interaction with actin (Harbeck, B. et al. 2000). In smooth muscle cells, phosphorylation of VASP on serine 157 promotes proliferation (Chen, L. et al. 2004). |
Immunogen | Immunogen: Phospho specific-peptide corresponding to residues surrounding serine 157 of human VASP |
Other Names | [VASP (pSer157)], [VASP; VASP; VASP] |
Gene, Accession # | [VASP], Gene ID: 7408, NCBI: NP_003361.1, UniProt: P50552 |
Catalog # | MBS225575 |
Price | $375 |
Order / More Info | VASP (pSer157) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |