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Antigenic Specificity | CDCA7L (C-term), 290-317 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.49 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This CDCA7L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 290-317 amino acids from the C-terminal region of human CDCA7L. Plays a role in transcriptional regulation as a repressor that inhibits monoamine oxidase A (MAOA) activity and gene expression by binding to the promoter. Plays an important oncogenic role in mediating the full transforming effect of MYC in medulloblastoma cells. Involved in apoptotic signaling pathways; May act downstream of P38-kinase and BCL-2, but upstream of CASP3/caspase-3 as well as CCND1/cyclin D1 and E2F1. |
Immunogen | n/a |
Other Names | [CDCA7L;HR1; JPO2; R1; Cell division cycle-associated 7-like protein; Cell division cycle-associated 7-like protein; Protein JPO2; Cell division cycle-associated 7-like protein; Transcription factor RAM2] |
Gene, Accession # | [CDCA7L], Gene ID: 55536, NCBI: NP_001120842.1, UniProt: B3KTR5 |
Catalog # | MBS9214475 |
Price | $165, $370 |
Order / More Info | CDCA7L (C-term), 290-317 Antibody from MYBIOSOURCE INC. |
Product Specific References | Huang A., et al. Cancer Res. 65:5607-5619(2005). Chen K., et al. J. Biol. Chem. 280:11552-11559(2005). Cathomen T., et al. Submitted (OCT-2002) to the EMBL/GenBank/DDBJ databases. Ota T., et al. Nat. Genet. 36:40-45(2004). Scherer S.W., et al. Science 300:767-772(2003). |