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Antigenic Specificity | TF2H2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total TF2H2 protein. Component of the core-TFIIH basal transcription factor involved in nucleotide excision repair (NER) of DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. The N-terminus interacts with and regulates XPD whereas an intact C-terminus is required for a successful escape of RNAP II form the promoter.Humbert S., EMBO J. 13:2393-2398(1994).The MGC Project Team, Genome Res. 14:2121-2127(2004).van der Steege G., Eur. J. Hum. Genet. 3:87-95(1995). |
Immunogen | Immunogen Type: Peptide Immunogen Description: Synthesized peptide derived from N-terminal of human TF2H2. |
Other Names | [TFIIH basal transcription factor complex p44 subunit; Basic transcription factor 2 44 kDa subunit; BTF2-p44; General transcription factor IIH polypeptide 2; GTF2H2] |
Gene, Accession # | [TF2H2], Gene ID: 2966, NCBI: NP_001506.1, UniProt: Q13888 |
Catalog # | MBS9411245 |
Price | $200, $255 |
Order / More Info | TF2H2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |