PDL-1 Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | PDL-1 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mg |
| Concentration | 1 mg/mL |
| Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry-Paraffin (IHC-P), Immunofluorescence (IF), Flow Cytometry (FC/FACS) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: PDL-1 antibody has no cross-reactivity to PDL-2. PD-L1 Antibody: Cell-mediated immune responses are initiated by T lymphocytes that are themselves stimulatedby cognate peptides bound to MHC molecules on antigen-presenting cells (APC). T-cell activation is generallyself-limited as activated T cells express receptors such as PD-1 (also known as PDCD-1) that mediate inhibitorysignals from the APC. PD-1 can bind two different but related ligands, PD-L1 and PD-L2. PD-L1 is a B7-relatedprotein that inhibits cell-mediated immune responses by reducing the secretion of IL-2 and IL-10 from memory Tcells. This suggests that PD-L1 may be useful in reducing allogenic CD4+ memory T-cell responses toendothelial cells, thereby reducing t |
| Immunogen | Immunogen: PDL-1 antibody was raised against a 17 amino acid synthetic peptide from near the center of human PDL-1. Buffer: PD-L1 Antibody is supplied in PBS containing 0.02% sodium azide. |
| Other Names | [PD-L1 : B7-H, B7H1, PDL1, PD-L1, PDCD1L1, PDCD1LG1, Programmed cell death 1 ligand 1, B7homolog 1], [CD274; CD274; B7-H; B7H1; PDL1; PD-L1; PDCD1L1; PDCD1LG1; B7H1; PDCD1L1; PDCD1LG1; PDL1; PD-L1; PDCD1 ligand 1; Programmed death ligand 1; B7-H1] |
| Gene, Accession # | [CD274], Gene ID: 29126, NCBI: NP_054862, UniProt: Q9NZQ7 |
| Catalog # | MBS151123 |
| Price | $375 |
| Order / More Info | PDL-1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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