Human BH3 Interacting Domain Death Agonist Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Human BH3 Interacting Domain Death Agonist |
| Clone | [P4D3AT] |
| Host Species | Mouse |
| Reactive Species | n/a |
| Isotype | IgG1 k |
| Format | Protein G purified |
| Size | 0.005 mg, 0.02 mg, 0.1 mg |
| Concentration | n/a |
| Applications | ELISA (EIA), Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Introduction: BID accession number NP 001187 is a pro-apoptotic Bcl-2 protein having only the BH3 domain. In reaction to apoptotic signaling, BID interacts with another Bcl-2 family of cell death regulators, called Bax, they form a heterodimer resulting to the insertion of Bax into the outer mitochondrial membrane. Bax induces the opening of the mitochondrial voltage-dependent anion channel which leads to the release of cytochrome c and other pro-apoptotic factors from the mitochondria resulting in activation of caspases. BID is a mediator of mitochondrial damage induced by caspase-8 (CASP8). CASP8 cleaves BID, and the COOH-terminal part translocates to mitochondria where it triggers cytochrome c release. The major proteolytic product p15 B |
| Immunogen | Immunogen: Anti-human BID mAb is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with recombinant human BID amino acids 1-195 purified from E Coli. |
| Other Names | [BID; BH3 Interacting Domain Death Agonist, Mouse Human; BH3-interacting domain death agonist; p22 BID; BID; FP497; MGC15319; MGC42355], [BID; BID; FP497; BID] |
| Gene, Accession # | [BID], Gene ID: 637, NCBI: NP_001187.1 |
| Catalog # | MBS140216 |
| Price | $140, $205, $505 |
| Order / More Info | Human BH3 Interacting Domain Death Agonist Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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