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Antigenic Specificity | Human CD49d |
Clone | [4ABU49] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | unconjugated |
Size | 50 tests, 100 tests, 500 tests |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | 4ABU49 reacts with a-4 integrin chain, which is expressed as a heterodimer with either of b1 (CD29) or b7. The a4b1 integrin (VLA-4) is present on lymphocytes, monocytes, thymocytes, NK cells, dendritic cells, erythroblastic precursor but absent on normal red blood cells, platelets and neutrophils. The a4b1 integrin mediated binding to VCAM-1 (CD106) and the CS-1 region of fibronectin. CD49d is involved in multiple inflammatory responses through the regulation of lymphocyte migration and T cell activation; CD49d also is essential for the differentiation and traffic of hematopoietic stem cells.This clone is cross reactive with non-human primate. * Relevant to tumor progression and metastasis. |
Immunogen | n/a |
Other Names | n/a |
Gene, Accession # | [CD49d] |
Catalog # | MBS8500222 |
Price | $215, $280, $350 |
Order / More Info | Human CD49d Antibody from MYBIOSOURCE INC. |
Product Specific References | 1.Lobb RR, Hemler ME. (1994) J Clin Invest 94: 1722. 2.Arroyo AG et at., (1996) Cell 85:997. 3.Ennis E et at., (1993) J Exp Med 177:207. 4.Berlin C (1993) Cell 74: 185. |