Human CD49d Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHuman CD49d
Clone[4ABU49]
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG1
Formatunconjugated
Size50 tests, 100 tests, 500 tests
Concentrationn/a
ApplicationsFlow Cytometry (FC/FACS), Immunofluorescence (IF)
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Description4ABU49 reacts with a-4 integrin chain, which is expressed as a heterodimer with either of b1 (CD29) or b7. The a4b1 integrin (VLA-4) is present on lymphocytes, monocytes, thymocytes, NK cells, dendritic cells, erythroblastic precursor but absent on normal red blood cells, platelets and neutrophils. The a4b1 integrin mediated binding to VCAM-1 (CD106) and the CS-1 region of fibronectin. CD49d is involved in multiple inflammatory responses through the regulation of lymphocyte migration and T cell activation; CD49d also is essential for the differentiation and traffic of hematopoietic stem cells.This clone is cross reactive with non-human primate. * Relevant to tumor progression and metastasis.
Immunogenn/a
Other Namesn/a
Gene, Accession #[CD49d]
Catalog #MBS8500222
Price$215, $280, $350
Order / More InfoHuman CD49d Antibody from MYBIOSOURCE INC.
Product Specific References1.Lobb RR, Hemler ME. (1994) J Clin Invest 94: 1722. 2.Arroyo AG et at., (1996) Cell 85:997. 3.Ennis E et at., (1993) J Exp Med 177:207. 4.Berlin C (1993) Cell 74: 185.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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