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Antigenic Specificity | TLK1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rapidly and transiently inhibited by phosphorylation following the generation of DNA double-stranded breaks during S-phase. This is cell cycle checkpoint and ATM-pathway dependent and appears to regulate processes involved in chromatin assembly. Isoform 3 phosphorylates and enhances the stability of the t-SNARE SNAP23, augmenting its assembly with syntaxin. Isoform 3 protects the cells from the ionizing radiation by facilitating the repair of DSBs. In vitro, phosphorylates histone H3 at 'Ser-10'. |
Immunogen | Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 160-230 of human TLK1 (NP 036422.3). |
Other Names | [PKU-beta] |
Gene, Accession # | [TLK1], Gene ID: 9874, NCBI: NP_001130026.1, UniProt: Q9UKI8 |
Catalog # | MBS8549639 |
Price | $280 |
Order / More Info | TLK1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |