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Antigenic Specificity | Tgfb1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse |
Isotype | n/a |
Format | peroxidase (HRP) conjugate |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Multifunctional protein that controls proliferation, differentiation and other functions in many cell types. Many cells synthesize TGFB1 and have specific receptors for it. It positively and negatively regulates many other growth factors. It plays an important role in bone remodeling as it is a potent stimulator of osteoblastic bone formation, causing chemotaxis, proliferation and differentiation in committed osteoblasts. Can promote either T-helper 17 cells (Th17) or regulatory T-cells (Treg) lineage differentiation in a concentration-dependent manner. At high concentrations, leads to FOXP3-mediated suppression of RORC and down-regulation of IL-17 expression, favoring Treg cell development. At low concentrations in concert with IL-6 and IL |
Immunogen | Immunogen: Recombinant Mouse Transforming growth factor beta-1 protein (30-391AA) |
Other Names | [Transforming growth factor beta-1TGF-beta-1; Tgfb1] |
Gene, Accession # | [Tgfb1], Gene ID: 21803, NCBI: NP_035707.1, UniProt: P04202 |
Catalog # | MBS7049273 |
Price | $160, $235 |
Order / More Info | Tgfb1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |