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Antigenic Specificity | TIA1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of TIA1 protein. The product encoded by TIA1 is a member of a RNA-binding protein family and possesses nucleolytic activity against cytotoxic lymphocyte (CTL) target cells. It has been suggested that this protein may be involved in the induction of apoptosis as it preferentially recognizes poly(A) homopolymers and induces DNA fragmentation in CTL targets. The major granule-associated species is a 15-kDa protein that is thought to be derived from the carboxyl terminus of the 40-kDa product by proteolytic processing. Alternative splicing resulting in different isoforms has been found for TIA1. |
Immunogen | Immunogen: Synthesized peptide derived from part region of human TIA1 protein at amino acid sequence of 201-250 |
Other Names | [Rabbit TIA1; Nucleolysin TIA-1 isoform p40; RNA-binding protein TIA-1; T-cell-restricted intracellular antigen-1; TIA-1; p40-TIA-1] |
Gene, Accession # | [TIA1], Gene ID: 7072, NCBI: P31483.3, UniProt: P31483 |
Catalog # | MBS9711204 |
Price | $130, $220, $325 |
Order / More Info | TIA1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |