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Antigenic Specificity | PCAF (N-term), 253-283 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human (predicted reactivity: mouse) |
Isotype | n/a |
Format | purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 2 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This PCAF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 253-283 amino acids from the N-terminal region of human PCAF. CBP and p300 are large nuclear proteins that bind to manysequence-specific factors involved in cell growth and/ordifferentiation, including c-jun and the adenoviral oncoproteinE1A. The protein encoded by this gene associates with p300/CBP. Ithas in vitro and in vivo binding activity with CBP and p300, andcompetes with E1A for binding sites in p300/CBP. It has histoneacetyl transferase activity with core histones and nucleosome coreparticles, indicating that this protein plays a direct role intranscriptional regulation. |
Immunogen | n/a |
Other Names | [Histone acetyltransferase KAT2B; Histone acetyltransferase PCAF; Histone acetylase PCAF; Lysine acetyltransferase 2B; P300/CBP-associated factor; P/CAF; KAT2B; PCAF] |
Gene, Accession # | [KAT2B], Gene ID: 8850, NCBI: NP_003875.3, UniProt: Q92831 |
Catalog # | MBS9205225 |
Price | $165, $370 |
Order / More Info | PCAF (N-term), 253-283 Antibody from MYBIOSOURCE INC. |
Product Specific References | Perez, R.E., et al. J. Cell. Physiol. 225(2):394-405(2010) Mooney, S.M., et al. J. Biol. Chem. 285(40):30443-30452(2010) Aoyama, T., et al. J. Biol. Chem. 285(39):29842-29850(2010) Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) : Shimahara, A., et al. J. Biol. Chem. 285(22):16967-16977(2010) |